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| 人CD26抗原產(chǎn)品介紹(中英文版） |
 品牌：原鑫生物
貨號(hào)：CU69
規(guī)格：10ug-100ug/￥1200
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Recombinant Human DPPIV/CD26 人CD26抗原產(chǎn)品介紹(中英文版） 
人CD26抗原產(chǎn)品介紹產(chǎn)品說(shuō)明(Description) Recombinant Human Dipeptidyl Peptidase 4 is produced by our Mammalian expression system and the target gene encoding Asn29-Pro766 is expressed with a Fc tag at the N-terminus. Accession #: P27487 Known as: Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26
人CD26抗原產(chǎn)品介紹制劑（Formulation） Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
人CD26抗原產(chǎn)品介紹質(zhì)量控制（Quality Control）
Purity: Greater than 95% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
人CD26抗原產(chǎn)品介紹運(yùn)輸(Shipping)
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
人CD26抗原產(chǎn)品介紹保存(Storage)
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
人CD26抗原產(chǎn)品介紹背景（Background）
CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. CD26 is expressed specifically in lymphatic vessels but not in blood vessels in the skin, small intestine, esophagus, ovary, breast and prostate glands. It acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. It may be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, it enhanced cell proliferation, a process inhibited by GPC3. It acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the cir
產(chǎn)品說(shuō)明(（描述） 重組人二肽基肽酶4由我們的哺乳動(dòng)物表達(dá)系統(tǒng)產(chǎn)生，編碼Asn29-Pro766的靶基因在N末端用Fc標(biāo)簽表達(dá) 加入#：P27487 稱為：二肽基肽酶4；ADABP公司；腺苷脫氨酶復(fù)合蛋白2；ADCP-2型；二肽基肽酶IV；民進(jìn)黨四號(hào)；T細(xì)胞活化抗原CD26 制劑（（配方） 作為0.2μm PBS過(guò)濾溶液提供，pH7.4。 質(zhì)量控制（質(zhì)量控制） 純度：經(jīng)還原SDS-PAGE測(cè)定大于95%。 內(nèi)毒素：經(jīng)鱟試劑檢測(cè)，小于0.1ng/ug（1eu/ug）。 運(yùn)輸(運(yùn)輸） 產(chǎn)品采用干冰/極地包裝運(yùn)輸 收到后，立即在下列溫度下儲(chǔ)存。 保存(儲(chǔ)存） 儲(chǔ)存于≤-70°C，收到后穩(wěn)定6個(gè)月。 儲(chǔ)存于≤-70°C，打開后在無(wú)菌條件下穩(wěn)定3個(gè)月 請(qǐng)盡量減少凍融循環(huán) 背景（背景） CD26是肽酶S9B家族Ⅱ型膜蛋白的信號(hào)錨定。CD26在淋巴管中特異表達(dá)，但在皮膚、小腸、食管、卵巢、乳腺和前列腺的血管中不表達(dá)。它通過(guò)至少結(jié)合ADA、CAV1、IGF2R和PTPRC作為T細(xì)胞共激活的正調(diào)節(jié)因子。它與CAV1和CARD11結(jié)合，以T細(xì)胞受體/CD3依賴的方式誘導(dǎo)T細(xì)胞增殖和NF-κB活化。它與ADA的相互作用也調(diào)節(jié)淋巴細(xì)胞與上皮細(xì)胞的粘附。FAP參與細(xì)胞外基質(zhì)（ECM）的細(xì)胞周蛋白水解，內(nèi)皮細(xì)胞向ECM的遷移和侵襲。它可能參與促進(jìn)淋巴管內(nèi)皮細(xì)胞粘附、遷移和小管形成。當(dāng)過(guò)表達(dá)時(shí)，它促進(jìn)細(xì)胞增殖，這一過(guò)程被GPC3抑制。它也是一種絲氨酸外肽酶，具有二肽基肽酶活性，通過(guò)切割cir中的肽來(lái)調(diào)節(jié)各種生理過(guò)程
人CD26抗原產(chǎn)品鏈接：http://zhuluxx.com/products-284.html
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